The flexible, robust Microfluidizer® processors provide better processing results than can be attained from other cell disruption methods or technologies. Our high-pressure homogenizers are used to rupture a wide variety of cells with specific shear requirements.
By precisely controlling shear, our customers are able to use the lowest pressure possible to achieve target cell rupture rates. In addition, Microfluidizer® technology requires fewer passes and effectively cools the product with a heat exchanger. All of these factors combine to ensure maximum cell breakage and protein harvesting.
In E. coli and yeast applications, rupture rates of greater than 99% have been achieved with Microfluidizer® technology. In addition, we work with customers to ensure that the optimal pressure is used for each application to balance the rupture rate with maximum recovery of soluble protein. In the case of lysis of haploid S. Pombe, we determined that five passes was optimal.
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Microfluidics™, the manufacturer of Microfluidizer® high shear fluid processors, is a leader in the design and production of laboratory and commercial processing equipment used in the production of micro- and nano-scale materials for pharmaceutical, biotech, chemical and diverse industries.
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