Microfluidizer^® Technology for solvent-free production of liposomes

Liposomes are versatile nanoparticles that are commonly used for delivering both Active Pharmaceutical Ingredients (API) and vaccines.

Traditional methods of creating liposomes involves using solvents which have to be removed, causing additional steps in the processing and extra health & safety
considerations.

A new process has been developed that can produce liposomes without the use of solvents. It has been described in a published scientific paper: Scalable solvent-free
production of liposomes. The paper lays out a path for producing liposomes in a greener way which is capable of being scaled for mass-production scale, whilst maintaining high drug encapsulation levels.

This Application Note summarizes the key points from the scientific paper.