Nanoparticle formulation system
Simple plug & play with microfluidics
We are delighted to partner with Inside Therapeutics to bring TAMARA to the R&D community in the USA & Canada
Streamline your drug development with a microfluidic-based platform that offers the precise synthesis of polymer and lipid-based nanoparticles such as LNPs, Liposomes & PLGAs.
TAMARA is the only platform that offers a comprehensive R&D system covering low volumes for screening (200µL) all the way up to in-vivo scale production (30mL batches). Furthermore, the innovative fluidic design eliminates head & tail losses, resulting in zero formulation losses.
Simple to use with an easy plug & play 3-step set up, samples can be processed in under 2 minutes. Reusable microfluidic chips make it a sustainable choice with low cost per run.
To learn more about TAMARA and its features, download the brochure.
Herringbone Mixer
This is the most commonly used format for micromixers as it offers the best flexibility in mixing time control, which dictates the size of the nanoparticles produced. It provides not only repeatability and uniformity, but also a large flow rate range which works with small & large volumes.
The mixing relies on the creation of micro-vortices in a ridged microchannel, where the two streams of reagent are injected. These induce a folding of the 2 liquid phases in on themselves, increasing the exchange surface between the 2 phases.
Baffle Mixer
The Baffle Mixer is offered as an alternative as it provides faster mixing using Dean vortices with higher pressure on the outside of the bend and lower pressure on the inner side providing centripetal acceleration for the flow to follow the curve.
This mixer method enables smaller nanoparticles to be produced at a higher total flow rate compared to Herringbone mixing.